Scientific Report 2010 Vidal (258.24 kB)

Key Publications

Cordero J, Macagno JP, Stefanatos R, Strathdee K, Cagan R, Vidal M (2010). Oncogenic Ras diverts a host TNF tumor suppressor activity into tumor promoter. Developmental Cell, in press.

Cordero J, Vidal M, Sansom O (2009). APC as a master regulator of intestinal homeostasis and transformation: From flies to vertebrates. Cell Cycle 8, 2926-31.

Vidal M, Warner S, Read RD, Cagan R (2007). Differing Src signaling levels have distinct outcomes in Drosophila. Cancer Res. 67, 10278-85.

Vidal M, Larson DE, Cagan R (2006). Csk-deficient cells are eliminated from normal Drosophila epithelia by exclusion, migration and apoptosis. Dev Cell. 10, 33-44.

Vidal M, Cagan R (2006). Drosophila models for cancer research. Current Opinion in Genetics and Development 16, 10-6.

Vidal M, Wells S, Ryan A, Cagan R (2005). ZD6474 suppresses oncogenic RET isoforms in a Drosophila model for type 2 multiple endocrine neoplasia syndromes and papillary thyroid carcinoma. Cancer Res. 65, 3538-41.

Education and qualifications
2003: PhD, National University of Rosario (UNR), Argentina
1999: MSc, ‘Licenciatura en Biotecnología’ (Biotechnology), UNR, Argentina

Appointments
2009-present: Group Leader, Beatson Institute for Cancer Research
2007-2009: Postdoctoral Fellow with Ross Cagan, Mount Sinai School of Medicine, USA
2003-2007: Postdoctoral Fellow with Ross Cagan, Washington University, USA

Honours and awards
Mount Sinai School of Medicine Award for Best Postdoctoral Paper in 2007 (Vidal M et al., Cancer Res. 67, 10278-85)

2011
Heller E, Hurchla MA, Xiang J, Chen S, Schneider J, Joeng K, Vidal M, Goldberg L, Deng H, Hornick MC, Prior JL, Piwnica-Worms D, Long F, Cagan R, Weilbaecher KN. Hedgehog signaling inhibition blocks growth of resistant tumors through effects on tumor microenvironment. Cancer Res doi: 10.1158/0008-5472.CAN-11-2681, published online 20 Dec 2011

Sandilands E, Serrels B, McEwan DG, Morton JP, Macgno JP, McLeod K, Stevens C, Brunton VG, Langdon WY, Vidal M, Sansom OJ, Dikic I, Wilkinson S, Frame MC. Autophagic targeting of SRC promotes cancer cell survival upon reduced FAK signalling. Nature Cell Biol doi:10.1038/ncb2386, published online 4 Dec 2011

Parisi F, Vidal M. Epithelial delamination and migration: lessons from Drosophila. Cell Adh Migr 2011; 5: 366-72

Stefanatos RK, Vidal M. Tumor invasion and metastasis in Drosophila: A bold past, a bright future. J Genet Genomics 2011; 38: 431-8
 
2010
Cordero J, Macagno JP, Stefanatos R, Strathdee K, Cagan R, Vidal M (2010). Oncogenic Ras diverts a host TNF tumor suppressor activity into tumor promoter. Developmental Cell 18, 999-1011.

Vidal M, Salavaggione L, Ylagan L, Wilkins M, Watson M, Weilbaecher K, Cagan, R (2010). A Role for the Epithelial Microenvironment at Tumor Boundaries. Evidence from Drosophila and Human Squamous Cell Carcinomas. Am J Pathol. 176, 3007-14.

Vidal M (2010). The dark side of fly TNF: an ancient developmental proof reading mechanism turned into tumor promoter. Cell Cycle 9, 3851-6.

2009
Cordero J, Vidal M, Sansom O (2009). APC as a master regulator of intestinal homeostasis and transformation: From flies to vertebrates. Cell Cycle 8, 2926-31.

2007
Vidal M, Warner S, Read RD, Cagan R (2007). Differing Src signaling levels have distinct outcomes in Drosophila. Cancer Res. 67, 10278-85.

2006
Krapf D, Vidal M, Arranz SE, Cabada MO (2006). Characterization and biological properties of L-HGP, a glycoprotein from the Amphibian oviduct with acrosome stabilizing effects. Biol Cell. 98, 403-13.

Vidal M, Larson DE, Cagan R (2006). Csk-deficient cells are eliminated from normal Drosophila epithelia by exclusion, migration and apoptosis. Dev Cell. 10, 33-44.

Vidal M, Cagan R (2006). Drosophila models for cancer research. Current Opinion in Genetics and Development 16, 10-6.

2005
Vidal M, Wells S, Ryan A, Cagan R (2005). ZD6474 suppresses oncogenic RET isoforms in a Drosophila model for type 2 multiple endocrine neoplasia syndromes and papillary thyroid carcinoma. Cancer Res. 65, 3538-41.