Case Studies

The CRUK Beatson Institute is highly collaborative and focuses on making discoveries that increase our understanding of cancer as a systemic disease. Our vision is the development and integration of key advanced technologies to tackle important questions in cancer biology with the goal of preventing and treating the disease. By understanding the fundamental mechanisms that drive cancer, both at early and late stages of the disease, we hope to uncover new preventative and therapeutic approaches. Each of these case studies describes work done here at the Beatson over the last five years, since 2017, towards this vision. They highlight our collaborative ethos, key research themes and some of our most significant outputs.

Case Study 1: Understanding the biology of early disease in an array of human malignancies

Case Study 2: Understanding metabolic vulnerabilities in vivo

Case Study 3: Targeting translational control for cancer therapy

Case Study 4: Membrane trafficking – a key player in metastasis

Case Study 5: Understanding how metabolism influences tumour invasiveness and the microenvironment

Case Study 6: Reprogramming neutrophils to suppress metastasis and enable immunotherapy