Postdoctoral Research Scientist - Prof Kevin Ryan

Regulation of autophagy in tumour development

Beatson Lab: Tumour Cell Death 

Salary: from £32,868 to £42,717 subject to experience, plus relocation allowance and visa costs if required.

Contract term: Fixed up to 6 years, subject to successful review at Year 3

About us

The CRUK Beatson Institute where the lab is based is a world leading cancer research institute, situated in the vibrant city of Glasgow in Scotland and hosting approximately 60 postdoctoral researcher scientists at any one time. It has an excellent reputation for fundamental cancer research, including world-class metabolism studies and renowned in vivo modelling of tumour growth and metastasis.

Project outline

A postdoctoral position is offered in the Tumour Cell Death and Autophagy Laboratory (TCDAL) headed by Professor Kevin Ryan. The TCDAL is a vibrant internationally-recognized team, which aims to understand how cells live, grow and die during tumour development and in response to cancer therapy. We focus on cell metabolism, autophagy and apoptosis, and the interplay between oncogenes and tumour suppressors in the control of tumour cell growth and survival The successful applicant will use cell biology, genetics and if appropriate, in vivo techniques to investigate how autophagy is regulated during tumour development to invoke both tumour suppressive and tumour promoting effects at different stages of disease. Prior experience/knowledge of epigenetics would be an advantage but is not essential.

Key recent publications from the group include: Barthet et al. Science Advances (23):eabf9141; Sierra Gonzalez et al. Nature 563(7733):719-723; Sakamaki et al. Molecular Cell 66(4):517-543; Rosenfeldt et al. Nature 504(7479):296-30; Long et al. Molecular Cell 50(3):394-406;

Applicants must have a PhD in a relevant field, be ambitious and be driven by scientific curiosity. Existing skills with regard to mammalian cell culture and molecular biology are desired and experience or interest in in vivo cancer models would be an advantage but is not essential.

For informal enquiries, please email Professor Kevin Ryan,

Postdoc support

Postdocs are key members of our research community, and we offer them a range of opportunities to train and develop as researchers while they are with us:

  • Exciting, innovative cancer research projects in state-of-the art labs
  • A highly collaborative and interactive research environment
  • Access to and training in key advanced technologies, for example imaging and in vivo modelling
  • A mentor enabling scheme to aid personal and professional development
  • A rich programme of scientific exchange through seminars, workshops and meetings
  • Support to make fellowship and small grant applications, including during their transition to their next position
  • Guidance and mentoring to compete for an independent scientist position as well as a multitude of other career options, including in industry.
  • A highly engaged postdoc society, providing peer support, training, careers advice and regular social events

Equality, Diversity and Inclusion

Our overarching research ethos at the Institute is about excellence, honesty, openness, accountability and integrity. The diversity of our staff and students is also what makes the Institute such a vibrant place to work and advance discoveries in cancer research. Family friendly policies, our collaborative ethos, a focus on good mental health and well-being and opportunities for all help to create an enjoyable and inclusive workplace where your voice matters.

The Institute is also committed to increasing the number of female scientists at the postdoc level and beyond and encourages female applicants to apply. We have a highly attractive maternity policy which provides 12-18 months support and funding for postdocs wishing to take time off to spend with their children amongst other family friendly policies.

Employee Benefits

  • Competitive salary
  • 40.5 days annual leave including bank holidays (pro-rata)
  • Defined Contribution pension scheme
  • Life Insurance scheme
  • Employee Assistance Programme
  • Season ticket loan
  • Additional maternity pay at 6 month's full pay (subject to service)
  • Shared parental leave
  • Cycle to work scheme that could save you 26-40% on a bike and accessories.
  • Access to Employee benefit schemes with discounts on supermarkets, cinema, travel and much more.
  • On-site secure parking

Closing date for Applications: 31 March 2023 but we will contact promising candidates on a rolling basis, so please apply as soon as you are ready.